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Comment
. 2018 Jul;84(7):1622-1623.
doi: 10.1111/bcp.13592. Epub 2018 Apr 24.

Kuypers and Vanhove reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker

Dirk R J Kuypers  1 , Thomas Vanhove
Affiliations
Comment

Kuypers and Vanhove reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker

Dirk R J Kuypers et al. Br J Clin Pharmacol. 2018 Jul.
No abstract available

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References

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    1. Storset E, Hole K, Midtvedt K, Bergan S, Molden E, Asberg A. The CYP3A biomarker 4β‐hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. Br J Clin Pharmacol 2017; 83: 1457–1465. - PMC - PubMed
    1. Tomalik‐Scharte D, Lutjohann D, Doroshyenko O, Frank D, Jetter A, Fuhr U. Plasma 4β‐hydroxycholesterol: an endogenous CYP3A metric? Clin Pharmacol Ther 2009; 86: 147–153. - PubMed
    1. Vanhove T, de Jonge H, de Loor H, Annaert P, Diczfalusy U, Kuypers DRJ. Comparative performance of oral midazolam clearance and plasma 4β‐hydroxycholesterol to explain interindividual variability in tacrolimus clearance. Br J Clin Pharmacol 2016; 82: 1539–1549. - PMC - PubMed

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