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Case Reports
. 2018 Apr-Jun;10(2):245-247.
doi: 10.4103/JLP.JLP_179_17.

Aggressive angiomyxoma in pregnancy: A rare and commonly misdiagnosed entity

Kamal Malukani  1 , Amit V Varma  1 , Devashish Choudhary  1 , Shilpi Dosi  1
Affiliations
Case Reports

Aggressive angiomyxoma in pregnancy: A rare and commonly misdiagnosed entity

Kamal Malukani et al. J Lab Physicians. 2018 Apr-Jun.

Abstract

Aggressive angiomyxoma (AAM) is an uncommon mesenchymal tumor that predominantly involves the pelvis and perineum of young females. It is often clinically mistaken for more common superficial lesions such as vaginal cysts, labial cysts, and lipomas. A review of the medical literature reveals very few cases of AAM reported in pregnancy. We describe a rare case of AAM in pregnancy, clinically misdiagnosed as prolapsed cervical fibroid.

Keywords: Aggressive angiomyxoma; mesenchymal tumors; pregnancy.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Magnetic resonance imaging: mass exhibits hyperintense signal on T2 and hypointense signals on T1 with multiple specks of T1 hyperintensity. (b) Photograph showing solid, homogeneous gray-white mass with glistening appearance
Figure 2
Figure 2
(a and b) Photomicrographs showing tumor composed of admixture of loose fibroareolar tissue with numerous variable-sized vessels and stellate reticulum cells on myxoid background (H and E, ×40). (c) Photomicrograph showing positive nuclear staining for estrogen receptors in immunohistochemistry. (d) Photomicrograph showing positive nuclear staining for vimentin in immunohistochemistry
See this image and copyright information in PMC

References

    1. Steeper TA, Rosai J. Aggressive angiomyxoma of the female pelvis and perineum. Report of nine cases of a distinctive type of gynecologic soft-tissue neoplasm. Am J Surg Pathol. 1983;7:463–75. - PubMed
    1. Salman MC, Kuzey GM, Dogan NU, Yuce K. Aggressive angiomyxoma of vulva recurring 8 years after initial diagnosis. Arch Gynecol Obstet. 2009;280:485–7. - PubMed
    1. Blandamura S, Cruz J, Faure Vergara L, Machado Puerto I, Ninfo V. Aggressive angiomyxoma: A second case of metastasis with patient's death. Hum Pathol. 2003;34:1072–4. - PubMed
    1. Bagga R, Keepanasseril A, Suri V, Nijhawan R. Aggressive angiomyxoma of the vulva in pregnancy: A case report and review of management options. MedGenMed. 2007;9:16. - PMC - PubMed
    1. Goyal P, Agrawal D, Sehgal S, Ghosh S, Kumar A, Singh S, et al. Aggressive angiomyxoma in pregnancy. Rare Tumors. 2014;6:5362. - PMC - PubMed

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