Biomarkers in Cardiorenal Syndromes
- PMID: 29693019
- PMCID: PMC5859843
- DOI: 10.1155/2018/9617363
Biomarkers in Cardiorenal Syndromes
Abstract
There is a consensus that cardiorenal syndromes (CRS) are defined as the disorders of heart and kidney where acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in another. Patients with CRS have increased hospitalization and mortality rates, and thus their identification is of great implication. Biomarkers are not only predictive in heart failure or renal diseases, but also useful in identifying cardiac dysfunction in renal diseases and renal injury in heart failure. Thus, they may be applied in order to identify patients with CRS and even assess prognosis and guide therapy in these patients. However, studies on biomarkers have just begun in CRS. Future studies are essential to observe current biomarkers and find novel biomarkers in CRS so as to improve diagnosis, therapy, and prognosis of CRS.
Similar articles
-
Protein biomarkers for cardiorenal syndrome.Expert Rev Proteomics. 2019 Apr;16(4):325-336. doi: 10.1080/14789450.2019.1592682. Epub 2019 Mar 22. Expert Rev Proteomics. 2019. PMID: 30855192 Review.
-
Biomarkers for acute cardiorenal syndrome.Nephrology (Carlton). 2018 Oct;23 Suppl 4:68-71. doi: 10.1111/nep.13473. Nephrology (Carlton). 2018. PMID: 30298648 Review.
-
Cardiorenal Interactions.Heart Fail Clin. 2016 Jul;12(3):335-47. doi: 10.1016/j.hfc.2016.03.002. Heart Fail Clin. 2016. PMID: 27371511 Review.
-
Cardiorenal Syndrome: New Pathways and Novel Biomarkers.Biomolecules. 2021 Oct 26;11(11):1581. doi: 10.3390/biom11111581. Biomolecules. 2021. PMID: 34827580 Free PMC article. Review.
-
Kidney injury molecule-1 and N-acetyl-β-D-glucosaminidase in chronic heart failure: possible biomarkers of cardiorenal syndrome.Eur J Heart Fail. 2011 Oct;13(10):1104-10. doi: 10.1093/eurjhf/hfr102. Epub 2011 Aug 16. Eur J Heart Fail. 2011. PMID: 21846754
Cited by
-
NAD+ enhancers as therapeutic agents in the cardiorenal axis.Cell Commun Signal. 2024 Nov 8;22(1):537. doi: 10.1186/s12964-024-01903-4. Cell Commun Signal. 2024. PMID: 39516787 Free PMC article. Review.
-
Cardiorenal syndrome: Multi-organ dysfunction involving the heart, kidney and vasculature.Br J Pharmacol. 2020 Jul;177(13):2906-2922. doi: 10.1111/bph.15065. Epub 2020 May 13. Br J Pharmacol. 2020. PMID: 32250449 Free PMC article. Review.
-
Renal Biomarkers in Cardiovascular Patients with Acute Kidney Injury: A Case Report and Literature Review.Diagnostics (Basel). 2023 May 31;13(11):1922. doi: 10.3390/diagnostics13111922. Diagnostics (Basel). 2023. PMID: 37296774 Free PMC article. Review.
-
Evaluation of Individual Cardiovascular Risk in Pre-Dialysis CKD Patients by Using the Ratio of Calcium-Phosphorus Product to Estimated Glomerular Filtration Rate (Ca × P/eGFR).Biomedicines. 2025 Jan 19;13(1):235. doi: 10.3390/biomedicines13010235. Biomedicines. 2025. PMID: 39857818 Free PMC article.
-
Beyond the Cardiorenal Syndrome: Pathophysiological Approaches and Biomarkers for Renal and Cardiac Crosstalk.Diagnostics (Basel). 2022 Mar 22;12(4):773. doi: 10.3390/diagnostics12040773. Diagnostics (Basel). 2022. PMID: 35453821 Free PMC article. Review.
References
-
- Pickering J. W., Than M. P., Cullen L., et al. Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis. Annals of Internal Medicine. 2017;166(10):715–724. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources