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Review
. 2018 Mar 5:2018:9617363.
doi: 10.1155/2018/9617363. eCollection 2018.

Biomarkers in Cardiorenal Syndromes

Shihui Fu  1   2 , Shaopan Zhao  1 , Ping Ye  1 , Leiming Luo  1
Affiliations
Review

Biomarkers in Cardiorenal Syndromes

Shihui Fu et al. Biomed Res Int. .

Abstract

There is a consensus that cardiorenal syndromes (CRS) are defined as the disorders of heart and kidney where acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in another. Patients with CRS have increased hospitalization and mortality rates, and thus their identification is of great implication. Biomarkers are not only predictive in heart failure or renal diseases, but also useful in identifying cardiac dysfunction in renal diseases and renal injury in heart failure. Thus, they may be applied in order to identify patients with CRS and even assess prognosis and guide therapy in these patients. However, studies on biomarkers have just begun in CRS. Future studies are essential to observe current biomarkers and find novel biomarkers in CRS so as to improve diagnosis, therapy, and prognosis of CRS.

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References

    1. Ronco C., McCullough P., Anker S. D., et al. Cardio-renal syndromes: report from the consensus conference of the acute dialysis qualityinitiative. European Heart Journal. 2010;31(6):703–711. - PMC - PubMed
    1. Damman K., Testani J. M. The kidney in heart failure: An update. European Heart Journal. 2015;36(23):1437–1444. doi: 10.1093/eurheartj/ehv010. - DOI - PMC - PubMed
    1. Expert Group on Biomarkers. Biomarkers in Cardiology-Part 2: In Coronary Heart Disease, Valve Disease and Special Situations. Arquivos Brasileiros de Cardiologia Journal. 2015;104(5):337–346. - PMC - PubMed
    1. Pickering J. W., Than M. P., Cullen L., et al. Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis. Annals of Internal Medicine. 2017;166(10):715–724. - PubMed
    1. Takashio S., Nagai T., Sugano Y., et al. Persistent increase in cardiac troponin T at hospital discharge predicts repeat hospitalization in patients with acute decompensated heart failure. PLoS ONE. 2017;12(4) doi: 10.1371/journal.pone.0173336.e0173336 - DOI - PMC - PubMed

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