Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jul;22(Suppl 1):105-113.
doi: 10.1007/s10461-018-2121-6.

Mother-to-Child Transmission of HIV and HIV-Free Survival in Swaziland: A Community-Based Household Survey

Affiliations

Mother-to-Child Transmission of HIV and HIV-Free Survival in Swaziland: A Community-Based Household Survey

Caspian Chouraya et al. AIDS Behav. 2018 Jul.

Abstract

In Swaziland, no data are available on the rates of HIV infection and HIV-free survival among children at the end of the breastfeeding period. We performed a national crosssectional community survey of children born 18-24 months prior to the study, in randomly selected constituencies in all 4 administrative regions of Swaziland, from April to June 2015. Mother-to-child transmission (MTCT) of HIV and HIV-free survival rates were calculated for all HIV-exposed children. The overall HIV-free survival rate at 18-24 months was 95.9% (95% CI 94.1-97.2). The estimated proportion of HIV infected children among known HIV-exposed children was 3.6% (95% CI 2.4-5.2). Older maternal age, delivering at a health facility, and receiving antenatal antiretroviral drugs were independently associated with reduced risk for child infection or death. The Swaziland program for prevention of MTCT achieved high HIV-free survival (95.9%) and low MTCT (3.6%) rates at 18-24 months of age when Option A (infant prophylaxis) of the WHO 2010 guidelines was implemented.

Keywords: HIV-free survival; Mother-to-child transmission (MTCT) of HIV; Prevention of mother-to-child transmission (PMTCT) of HIV.

PubMed Disclaimer

Conflict of interest statement

Competing interests

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Flow chart of study participants.

References

    1. Joint United Nations Programme on HIV/AIDS (UNAIDS) [Accessed May 25, 2016];Fact sheet. 2015 http://www.unaids.org/en/resources/campaigns/HowAIDSchangedeverything/fa....
    1. Joint United Nations Programme on HIV/AIDS (UNAIDS) [Accessed June 30, 2016];2015 progress report on the global plan towards the elimination of new HIV infections among children and keeping their mothers alive. http://www.unaids.org/sites/default/files/media_asset/JC2774_2015Progres.... Published 2015.
    1. World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection recommendations for a public health approach second edition, 2016. Geneva, Switzerland: World Health Organization; [Accessed August 16, 2016]. http://www.who.int/hiv/pub/arv/arv-2016/en/. Published 2016.
    1. World Health Organization. [Accessed May 20, 2016];Antiretroviral drugs for treating pregnant women and preventing HIV infection in infants: recommendations for a public health approach. http://whqlibdoc.who.int/publications/2010/9789241599818_eng.pdf. Published 2010. - PubMed
    1. World Health Organization. [Accessed May 20, 2016];A short guide on methods: measuring the impact of national PMTCT programmes towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive. http://apps.who.int/iris/bitstream/10665/75478/1/9789241504362_eng.pdf. Published 2012.

MeSH terms

Substances