Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1988;31(2):73-4.

Twofold CuZnSOD activity suggesting homozygous submicroscopic duplication of chromosome 21 in the orangutan

J de Grouchy  1 , A Nicole, C Cochet, N Créau-Goldberg, P M Sinet
Affiliations
  • PMID: 2969695
Comparative Study

Twofold CuZnSOD activity suggesting homozygous submicroscopic duplication of chromosome 21 in the orangutan

J de Grouchy et al. Ann Genet. 1988.

Abstract

A twofold CuZnSOD activity was observed in an orangutan as compared to man and a chimpanzee. This suggests that a submicroscopic duplication of chromosome 21 (similar to those demonstrated in patients with the trisomy 21 phenotype but with a normal karyotype) has occurred in the homozygous state during evolution of the orangutan phylum. Such duplications could be important evolutionary mechanisms, together with visible chromosome rearrangements and classical gene mutations.

PubMed Disclaimer

Publication types

Substances