Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Aug 1;235(1-2):211-4.
doi: 10.1016/0014-5793(88)81264-x.

The hydrolysis of ATP that accompanies actin polymerization is essentially irreversible

M F Carlier  1 , D Pantaloni, J A Evans, P K Lambooy, E D Korn, M R Webb
Affiliations
Free article

The hydrolysis of ATP that accompanies actin polymerization is essentially irreversible

M F Carlier et al. FEBS Lett. .
Free article

Abstract

The hydrolysis of ATP that accompanies the polymerization of actin occurs on the F-actin subsequent to the addition of the G-ATP-actin subunit to the elongating filament. We now show that this ATP hydrolysis is essentially irreversible. Thus, a large decrease in free energy occurs at the cleavage step, F-ATP-actin----F-ADP-Pi-actin.

PubMed Disclaimer

LinkOut - more resources