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. 2005 Jul 28;4(3):197-201.
doi: 10.1111/j.1447-0578.2005.00105.x. eCollection 2005 Sep.

Elective single embryo transfer: Comparison of blastocyst and cleavage-stage embryo transfer

Toshihiro Kawamura  1 , Michiko Mori  1 , Akane Arichi  1 , Yuko Tajima  1 , Yasuhiro Karasawa  1 , Kahori Suga  1 , Sachiko Ikumi  1 , Seika Ishikawa  1 , Makiko Kawamura  1
Affiliations

Elective single embryo transfer: Comparison of blastocyst and cleavage-stage embryo transfer

Toshihiro Kawamura et al. Reprod Med Biol. .

Abstract

Objective: Blastocysts are reportedly suitable for preventing multiple pregnancies as a result of the high implantation rate per embryo. The present study compared clinical results for elective single embryo transfer (ET) between blastocysts and cleavage-stage embryos in order to ascertain the usefulness of blastocyst culturing in single ET. Methods: Between January 2002 and December 2004, conventional in vitro fertilization ET and/or intracytoplasmic sperm injection was carried out for single ET in 86 cycles, to prevent multiple pregnancies (for medical reasons or because of patient wishes). Results: Among the 80 cycles in which a fresh embryo was transferred, pregnancy/implantation rates per ET were 35.3% for day 2/3 ET and 50.0% for day 5 ET, and pregnancy/implantation rates per oocyte retrieval were 35.3% for day 2/3 ET and 44.2% for day 5 ET. Ongoing pregnancy/delivery rates per oocyte retrieval were 32.4% for day 2/3 ET and 38.5% for day 5 ET. Monozygotic twinning occurred in one case of day 5 ET. Conclusions: Pregnancy rates per single ET tended to be higher for day 5 ET than for day 2/3 ET. However, no marked differences were identified in ongoing pregnancy/delivery rates per oocyte retrieval between groups. (Reprod Med Biol 2005; 4: 197-201).

Keywords: blastocyst transfer; cleavage‐stage embryo transfer; single embryo transfer.

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References

    1. Fanchin R, Ayoubi JM, Righini C, Olivennes F, Schonauer LM, Frydman R. Uterine contractility decreases at the time of blastocyst transfers. Hum Reprod 2001; 16: 1115–1119. - PubMed
    1. Gardner DK, Lane M. Blastocyst transfer. Clin Obstet Gynecol 2003; 46: 231–238. - PubMed
    1. Behr B, Fisch JD, Racowsky C, Miller K, Pool TB, Milki AA. Blastocyst‐ET and monozygotic twinning. J Assist Reprod Genet 2000 July; 17: 349–351. - PMC - PubMed
    1. Milki AA, Jun SH, Hinckley MD, Behr B, Giudice LC, Westphal LM. Incidence of monozygotic twinning with blastocyst transfer compared to cleavage‐stage transfer. Fertil Steril 2003; 79: 503–506. - PubMed
    1. Gardner DK, Lane M. Culture and selection of viable blastocysts: a feasible proposition for human IVF? Hum Reprod Update 1997; 3: 367–382. - PubMed