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. 2007 Feb 16;6(1):53-57.
doi: 10.1111/j.1447-0578.2007.00165.x. eCollection 2007 Mar.

Clinical outcomes of two different endometrial preparation methods for cryopreserved-thawed embryo transfer in patients with a normal menstrual cycle

Toshihiro Kawamura  1 , Hiroshi Motoyama  1 , Atsushi Yanaihara  1 , Takeshi Yorimitsu  1 , Akane Arichi  1 , Yasuhiro Karasawa  1 , Kahori Suga  1 , Kaoru Miya  1 , Seika Ishikawa  1 , Shiho Mizushima  1 , Makiko Kawamura  1
Affiliations

Clinical outcomes of two different endometrial preparation methods for cryopreserved-thawed embryo transfer in patients with a normal menstrual cycle

Toshihiro Kawamura et al. Reprod Med Biol. .

Abstract

Aim: To compare the clinical outcomes of cryopreserved-thawed embryo transfer among patients with a normal menstrual cycle who had natural or hormone-replacement cycles. Methods: From January 2004 to June 2006, cryopreserved embryos following conventional in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) were thawed and transferred in a total of 720 natural cycles and 136 hormone-replacement cycles. Results: Cryopreserved-thawed embryo transfer in patients who had a natural or hormone-replacement cycle resulted in clinical pregnancy in 43.1% and 40.4%, respectively; a rate of miscarriage of 14.5% and 23.6%, respectively; and a rate of ongoing pregnancy and delivery of 36.5% and 30.9%, respectively. None of these differences were statistically significant. Conclusions: Patients with a normal menstrual cycle who have natural or hormone-replacement cycles can be expected to have comparable clinical outcomes with cryopreserved-thawed embryo transfer. (Reprod Med Biol 2007; 6: 53-57).

Keywords: hormone‐replacement cycle; cryopreserved‐thawed embryo transfer; natural cycle.

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