Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary?
- PMID: 29699796
- PMCID: PMC6063781
- DOI: 10.1016/j.jpeds.2018.03.003
Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary?
Abstract
The prevalence of nephrocalcinosis in persons with pseudohypoparathyroidism has not been systematically examined. We conducted a retrospective study of renal imaging and biochemical results in 19 patients with pseudohypoparathyroidism with 49 imaging assessments. No cases of nephrocalcinosis were identified. Routine screening for nephrocalcinosis in pseudohypoparathyroidism may not be necessary.
Keywords: PTH, phosphate; calcium; parathyroid hormone; pseudohypoparathyroidism.
Copyright © 2018 Elsevier Inc. All rights reserved.
Conflict of interest statement
The authors declare no conflicts of interest.
Comment in
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Prevalence of nephrocalcinosis in pseudohypoparathyroidism: Is screening necessary?J Pediatr. 2018 Aug;199:3. doi: 10.1016/j.jpeds.2018.06.027. J Pediatr. 2018. PMID: 30049397 No abstract available.
References
-
- Gejman PV, Weinstein LS, Martinez M, Spiegel AM, Cao Q, Hsieh WT, et al. Genetic mapping of the Gs-alpha subunit gene (GNAS1) to the distal long arm of chromosome 20 using a polymorphism detected by denaturing gradient gel electrophoresis. Genomics. 1991;9:782–3. - PubMed
-
- Rao VV, Schnittger S, Hansmann I. G protein Gs alpha (GNAS 1), the probable candidate gene for Albright hereditary osteodystrophy, is assigned to human chromosome 20q12–q13.2. Genomics. 1991;10:257–61. - PubMed
-
- Mantovani G, Spada A, Elli FM. Pseudohypoparathyroidism and Gsalpha-cAMP-linked disorders: current view and open issues. Nat Rev Endocrinol. 2016;12:347–56. - PubMed
-
- Gelfand IM, Eugster EA, DiMeglio LA. Presentation and clinical progression of pseudohypoparathyroidism with multi-hormone resistance and Albright hereditary osteodystrophy: a case series. The Journal of pediatrics. 2006;149:877–80. - PubMed
-
- Albright F, Burnett C, Smith P, Parson W. Pseudohypoparathyroidism: an example of “Seabright-Bantam syndrome”. Endocrinology. 1942;30:922–32.
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