Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Oct;103(10):e440-e442.
doi: 10.3324/haematol.2018.190967. Epub 2018 Apr 26.

Stability of fetal hemoglobin levels in patients receiving metformin therapy

Mohamed-Rachid Boulassel  1   2 , Abdal-Aziz Issa El-Hussain  3 , Moataz Mohamed Hassan  4 , Mohamed-Lamine Toumi  5 , Sameha Merzoug  5 , Zahra Al-Qarni  3 , Hammad Khan  2 , Zied Gaifer  6 , Khalil Al-Farsi  2 , Murtadha Al-Khabori  2 , Mohamed Al Huneini  2 , Salam Al-Kindi  2
Affiliations

Stability of fetal hemoglobin levels in patients receiving metformin therapy

Mohamed-Rachid Boulassel et al. Haematologica. 2018 Oct.
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Changes of hemoglobin F levels among study participants. Arrows indicate the time at which metformin therapy was started and ended. Cases from 1 to 3 and from 4 to 7 represent patients with polycystic ovarian syndrome and type 2 diabetes, respectively.
See this image and copyright information in PMC

References

    1. Zhang Y, Crosby JR, Boerwinkle E, Pace B, Sheehan VA. Pharmacological induction of FOXO3 is a potential treatment for sickle cell disease. Blood. 2015;126(23):282.
    1. Zhang Y, Weiss M, Sumazin P, Sheehan VA. Metformin induces FOXO3-dependent fetal hemoglobin production in primary erythroid cells. Blood. 2016;128(22):322. - PMC - PubMed
    1. Zhang Y, Paikari A, Sumazin P, et al. Metformin induction of fetal hemoglobin. Blood. 2017;130(Suppl1):359.
    1. Grossberg R, Zhang Y, Gross R. A time-to-prescription-refill measure of antiretroviral adherence predicted changes in viral load in HIV. J Clin Epidemiol. 2004;57(10):1107–1110. - PubMed
    1. Boulassel MR, Al-Farsi R, Al-Hashmi S, Al-Riyami H, Khan H, Al-Kindi S. Accuracy of platelet counting by optical and impedance methods in patients with thrombocytopaenia. Sultan Qaboos Univ Med J. 2015;15(4):e463–468. - PMC - PubMed

Publication types