No evidence for unknown archaic ancestry in South Asia

Pontus Skoglund^{1

2

3}, Swapan Mallick^{4

5

6}, Nick Patterson⁵, David Reich^{7

8

9}

Affiliations

¹ Department of Genetics, Harvard Medical School, Boston, MA, USA. pontus.skoglund@crick.ac.uk.
² Broad Institute of Harvard and MIT, Cambridge, MA, USA. pontus.skoglund@crick.ac.uk.
³ The Francis Crick Institute, London, UK. pontus.skoglund@crick.ac.uk.
⁴ Department of Genetics, Harvard Medical School, Boston, MA, USA.
⁵ Broad Institute of Harvard and MIT, Cambridge, MA, USA.
⁶ Howard Hughes Medical Institute, Boston, MA, USA.
⁷ Department of Genetics, Harvard Medical School, Boston, MA, USA. reich@genetics.med.harvard.edu.
⁸ Broad Institute of Harvard and MIT, Cambridge, MA, USA. reich@genetics.med.harvard.edu.
⁹ Howard Hughes Medical Institute, Boston, MA, USA. reich@genetics.med.harvard.edu.

PMID: 29700470
PMCID: PMC6433599
DOI: 10.1038/s41588-018-0097-9

Comment

No evidence for unknown archaic ancestry in South Asia

Pontus Skoglund et al. Nat Genet. 2018 May.

. 2018 May;50(5):632-633.

doi: 10.1038/s41588-018-0097-9.

Authors

Pontus Skoglund^{1

2

3}, Swapan Mallick^{4

5

6}, Nick Patterson⁵, David Reich^{7

8

9}

Affiliations

¹ Department of Genetics, Harvard Medical School, Boston, MA, USA. pontus.skoglund@crick.ac.uk.
² Broad Institute of Harvard and MIT, Cambridge, MA, USA. pontus.skoglund@crick.ac.uk.
³ The Francis Crick Institute, London, UK. pontus.skoglund@crick.ac.uk.
⁴ Department of Genetics, Harvard Medical School, Boston, MA, USA.
⁵ Broad Institute of Harvard and MIT, Cambridge, MA, USA.
⁶ Howard Hughes Medical Institute, Boston, MA, USA.
⁷ Department of Genetics, Harvard Medical School, Boston, MA, USA. reich@genetics.med.harvard.edu.
⁸ Broad Institute of Harvard and MIT, Cambridge, MA, USA. reich@genetics.med.harvard.edu.
⁹ Howard Hughes Medical Institute, Boston, MA, USA. reich@genetics.med.harvard.edu.

PMID: 29700470
PMCID: PMC6433599
DOI: 10.1038/s41588-018-0097-9

No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests

The authors declare no competing financial interests.

Figures

**Figure 1.. The key statistic used to support the claim of unknown archaic ancestry in Andamanese and mainland Indians by Mondal *et al.* is inconsistent with all previously published datasets.**
Evidence for unknown archaic ancestry in Andamanese and mainland Indians does not replicate in four previously published data sets. Error bars show 1 weighted block jackknife standard error on each side. All statistics except the one reported by Mondal *et al*. are consistent with no excess archaic admixture in South Asians (|Z| < 2).

See this image and copyright information in PMC

Comment on

Genomic analysis of Andamanese provides insights into ancient human migration into Asia and adaptation.
Mondal M, Casals F, Xu T, Dall'Olio GM, Pybus M, Netea MG, Comas D, Laayouni H, Li Q, Majumder PP, Bertranpetit J. Mondal M, et al. Nat Genet. 2016 Sep;48(9):1066-70. doi: 10.1038/ng.3621. Epub 2016 Jul 25. Nat Genet. 2016. PMID: 27455350

References

1. Green RE et al. A Draft Sequence of the Neandertal Genome. Science 328, 710–722 (2010). - PMC - PubMed
1. Reich D et al. Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature 468, 1053–1060 (2010). - PMC - PubMed
1. Mondal M et al. Genomic analysis of Andamanese provides insights into ancient human migration into Asia and adaptation. Nature Genetics (2016). - PubMed
1. Patterson N et al. Ancient admixture in human history. Genetics 192, 1065–1093 (2012). - PMC - PubMed
1. Skoglund P & Jakobsson M Archaic human ancestry in East Asia. Proceedings of the National Academy of Sciences (2011). - PMC - PubMed

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No evidence for unknown archaic ancestry in South Asia

Affiliations

No evidence for unknown archaic ancestry in South Asia

Authors

Affiliations

Conflict of interest statement

Figures

Comment on

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

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