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Review
. 2018 Jul;22(7):3323-3329.
doi: 10.1111/jcmm.13643. Epub 2018 Apr 26.

Telocytes and interstitial cells of Cajal in the biliary system

Lei Chen  1   2 , Baoping Yu  1   2
Affiliations
Review

Telocytes and interstitial cells of Cajal in the biliary system

Lei Chen et al. J Cell Mol Med. 2018 Jul.

Abstract

A novel type of interstitial tissue cells in the biliary tree termed telocytes (TCs), formerly known as interstitial Cajal-like cells (ICLCs), exhibits very particular features which unequivocally distinguish these cells from interstitial cells of Cajal (ICCs) and other interstitial cell types. Current research substantiates the existence of TCs and ICCs in the biliary system (gallbladder, extrahepatic bile duct, cystic duct, common bile duct and sphincter of Oddi). Here, we review the distribution, morphology and ultrastructure of TCs and ICCs in the biliary tree, with emphasis on their presumptive roles in physiological and pathophysiological processes.

Keywords: biliary system; extrahepatic bile ducts; gallbladder; interstitial cells of Cajal; telocytes.

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References

    1. Garcia‐Lopez P, Garcia‐Marin V, Martinez‐Murillo R, Freire M. Updating old ideas and recent advances regarding the interstitial cells of Cajal. Brain Res Rev. 2009;61:154‐169. - PubMed
    1. Faussone‐Pellegrini MS, Cortesini C, Romagnoli P. Ultrastructure of the tunica muscularis of the cardial portion of the human esophagus and stomach, with special reference to the so‐called Cajal's interstitial cells. Arch Ital Anat Embriol. 1977;82:157‐177. - PubMed
    1. Thuneberg L. Interstitial cells of Cajal: intestinal pacemaker cells? Adv Anat Embryol Cell Biol. 1982;71:1‐130. - PubMed
    1. Durdle NG, Kingma YJ, Bowes KL, et al. Origin of slow waves in the canine colon. Gastroenterology. 1983;84:375‐382. - PubMed
    1. Ward SM, Burns AJ, Torihashi S, et al. Mutation of the proto‐oncogene c‐kit blocks development of interstitial cells and electrical rhythmicity in murine. J Physiol. 1994;94:91‐97. - PMC - PubMed

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