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Clinical Trial
. 1988 Aug;11(4):431-4.
doi: 10.1097/00000421-198808000-00003.

High-dose medroxyprogesterone acetate plus mitomycin-C or vindesine in the treatment of advanced breast cancer

C I Falkson  1 , H C Falkson, G Falkson
Affiliations
Clinical Trial

High-dose medroxyprogesterone acetate plus mitomycin-C or vindesine in the treatment of advanced breast cancer

C I Falkson et al. Am J Clin Oncol. 1988 Aug.

Abstract

Forty women with metastatic breast cancer were randomized to receive either mitomycin-C (MMC) (21 patients) or vindesine (19 patients) with high dose medroxyprogesterone acetate (MPA). Response rates were not significantly different (33% for MPA and MMC and 28% for MPA and vindesine); the duration of response was better for patients receiving the MMC combination (median of 10.5 months versus 6 months for those on the vindesine combination).

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