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Case Reports
. 2018 Apr;97(17):e0424.
doi: 10.1097/MD.0000000000010424.

Intracranial hemorrhage associated with medulla oblongata dysplasia in a premature infant: A case report

Li-Na Jiang  1 , Mei-Chen Wei, Hong Cui
Affiliations
Case Reports

Intracranial hemorrhage associated with medulla oblongata dysplasia in a premature infant: A case report

Li-Na Jiang et al. Medicine (Baltimore). 2018 Apr.

Abstract

Rationale: Medulla oblongata dysplasia is an extremely rare form of neurodevelopmental immaturity in premature infants. Intracranial hemorrhage in premature infants may be closely related to neurodevelopmental immaturity.

Diagnoses: We report a female premature infant who succumbed to intracranial hemorrhage caused by medulla oblongata dysplasia.

Patient concerns: The infant was born at 31 weeks gestation. The onset manifestation was symptomatic epilepsy associated with subependymal hemorrhage.

Interventions: Levetiracetam and sodium valproate were administered. During the hospitalization, hydrocephalus developed and the intracranial hemorrhage aggravated.

Outcomes: The infant died on day 171 after birth.

Lessons: Early identification and prompt treatment should be emphasized. Clinicians should be aware of this condition, as it can potentially cause neonatal intracranial hemorrhage.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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References

    1. Mack LA, Wright K, Hirsch JH, et al. Intracranial hemorrhage in premature infants: accuracy in sonographic evaluation. AJR Am J Roentgenol 1981;137:245–50. - PubMed
    1. Israels SJ, Gilfix BM. Alpha1-antitrypsin deficiency with fatal intracranial hemorrhage in a newborn. J Pediatr Hematol Oncol 1999;21:447–50. - PubMed
    1. Oueriagli Nabih Z, Labib S, Harandou M. Delayed diagnosis of newborn vitamin K deficiency bleeding: from simple cutaneous lesion to intracranial hemorrhage. Arch Pediatr 2011;18:914–6. - PubMed
    1. Ucsel R, Savasan S, Coban A, et al. Fatal intracranial hemorrhage in a newborn with factor VII deficiency. Turk J Pediatr 1996;38:257–60. - PubMed
    1. Shankaran S. Intracranial hemorrhage in newborn infants. Indian J Pediatr 1983;50:353–62. - PubMed

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