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Comment
. 2018 May;41(5):244-247.
doi: 10.1016/j.tins.2018.03.004.

Understanding the Brain, By Default

James M Shine  1 , Michael Breakspear  2
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Understanding the Brain, By Default

James M Shine et al. Trends Neurosci. 2018 May.

Abstract

In 2001 Raichle and colleagues showed that, at rest, brain activity fluctuates near a metabolically active equilibrium: a 'default mode' of brain function. This finding broke ranks with the prevailing 'task-rest' dichotomy to position the brain as continuously active, balancing the deployment of resources according to current and anticipated needs.

Keywords: default mode; fMRI; oxygen extraction fraction; positron emission tomography; resting state.

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  • A default mode of brain function.
    Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. Raichle ME, et al. Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):676-82. doi: 10.1073/pnas.98.2.676. Proc Natl Acad Sci U S A. 2001. PMID: 11209064 Free PMC article.

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