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. 1988 Aug;3(2):225-9.

Identification of the protein product of the c-mos proto-oncogene in mouse testes

N K Herzog  1 , B Singh, J Elder, I Lipkin, R J Trauger, C F Millette, D S Goldman, H Wolfes, G M Cooper, R B Arlinghaus
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  • PMID: 2970613

Identification of the protein product of the c-mos proto-oncogene in mouse testes

N K Herzog et al. Oncogene. 1988 Aug.

Abstract

The mouse c-mos proto-oncogene RNA is expressed primarily in mouse gonadal tissues and embryos. Until now, the c-mos protein has not been identified. Utilizing two different site-directed affinity purified anti-peptide antibodies, we have identified a 43 kDa c-mos protein in mouse testes and in germ cell preparations derived from testes. This 43 kDa testicular protein was found to be structurally related to a bacterially expressed c-mos protein by peptide mapping. Immunoblots of whole mouse sections were employed to establish that the c-mos protein is expressed primarily in the testes.

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