In the Era of Precision Medicine and Big Data, Who Is Normal?
- PMID: 29710130
- PMCID: PMC7572221
- DOI: 10.1001/jama.2018.2009
In the Era of Precision Medicine and Big Data, Who Is Normal?
Conflict of interest statement
Comment in
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Using Big Data to Determine Reference Values for Laboratory Tests.JAMA. 2018 Oct 9;320(14):1495-1496. doi: 10.1001/jama.2018.10952. JAMA. 2018. PMID: 30304419 No abstract available.
References
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- Toward NRC. Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease. Washington, DC: National Academies Press; 2011. - PubMed
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- Ioannidis JPA. Are mortality differences detected by administrative data reliable and actionable? JAMA. 2013;309 (13):1410–1411. - PubMed
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- Clinical and Laboratory Standards Institute. Defining, establishing, and verifying reference intervals in the clinical laboratory; approved guideline. https://clsi.org/standards/products/method-evaluation/documents/ep28/. Accessed April 6, 2018.
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