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. 1998 Mar 2;37(4):489-492.
doi: 10.1002/(SICI)1521-3773(19980302)37:4<489::AID-ANIE489>3.0.CO;2-N.

N-Functionalized 1-Alkynylamides: New Building Blocks for Transition Metal Mediated Inter- and Intramolecular [2+2+1] Cycloadditions

Bernhard Witulski  1 , Thomas Stengel  1
Affiliations

N-Functionalized 1-Alkynylamides: New Building Blocks for Transition Metal Mediated Inter- and Intramolecular [2+2+1] Cycloadditions

Bernhard Witulski et al. Angew Chem Int Ed Engl. .

Abstract

A conceptually new, stereoselective approach to compounds such as 1 and 2 is expected from the so far unknown class of N-functionalized 1-alkynylamides. Building blocks of the type I and II can be applied to inter- and intramolecular, regio- and stereoselective [Co2 (CO)8 ]-mediated [2+2+1] cycloadditions.

Keywords: Alkynes; Carbenes; Cobalt; Cycloadditions; Heterocycles.

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