Organic Synthesis and Biological Signal Transduction

Abstract

The understanding of cellular communication pathways in molecular detail is an important goal of bioorganic research. The synthesis of analogues of active substances (e.g. 1) to study the regulation of muscle contraction or the specific lipid modification of representative peptides (→2) to investigate their subcellular, targeted transfer to intracellular membranes are examples of the capability of organic synthesis is in the research of biological signal transduction mechanisms.

Keywords: Bioorganic chemistry; Enzyme inhibitors; Peptide conjugates; Signal transduction; Synthetic methods.