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Review
. 1998 Dec 17;37(23):3220-3238.
doi: 10.1002/(SICI)1521-3773(19981217)37:23<3220::AID-ANIE3220>3.0.CO;2-C.

Nucleic Acid Nanostructures and Topology

Nadrian C Seeman  1
Affiliations
Review

Nucleic Acid Nanostructures and Topology

Nadrian C Seeman. Angew Chem Int Ed Engl. .

Abstract

Knots, polyhedra, and Borromean rings with specific structural and topological features can be made from DNA. Biotechnologists have been exploiting the programmability of DNA intermolecular associations for a quarter of a century. These operations have now been applied successfully to branched DNA species to produce complex target structures (for example, the cube shown in the picture) and a nanomechanical device. The assembly of two-dimensional crystals with programmed topographic characteristics demonstrates the simplicity of translating design into surface structures.

Keywords: Catenanes; DNA structures; Mechanical bonds; Nanostructures; Topochemistry.

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