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Review
. 1998 Sep 4;37(16):2162-2178.
doi: 10.1002/(SICI)1521-3773(19980904)37:16<2162::AID-ANIE2162>3.0.CO;2-2.

Lithistid Sponges: Star Performers or Hosts to the Stars

Carole A Bewley  1 , D John Faulkner  2
Affiliations
Review

Lithistid Sponges: Star Performers or Hosts to the Stars

Carole A Bewley et al. Angew Chem Int Ed Engl. .

Abstract

Extremely careful separation of the symbiotic bacteria from the cells of lithistid sponges has provided evidence that in the case of Theonella swinhoei the chemically diverse and biologically active metabolites, swinholide A and theopalauamide (1), are produced by symbionts. Marine sponges of the order Lithistida contain a diverse range of exotic natural products with valuable biological and pharmacological activities.

Keywords: Antifungal agents; Antitumor agents; Macrocycles; Natural products; Peptides.

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