Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1999 May 3;38(9):1172-1193.
doi: 10.1002/(SICI)1521-3773(19990503)38:9<1172::AID-ANIE1172>3.0.CO;2-C.

The Vancomycin Group of Antibiotics and the Fight against Resistant Bacteria

Dudley H Williams  1 , Ben Bardsley  1
Affiliations
Review

The Vancomycin Group of Antibiotics and the Fight against Resistant Bacteria

Dudley H Williams et al. Angew Chem Int Ed Engl. .

Abstract

A last line of defence against "superbugs" are the vancomycin group antibiotics. This review describes the determination of their mode of action, and a mechanism of resistance to them. Remarkably, this mechanism of resistance can be overcome without directly modifying the binding site of the antibiotics for the cell-wall precursors of pathogenic bacteria.

Keywords: Antibiotics; Cooperative effects; Dimerizations; Resistant bacteria; Vancomycin.

PubMed Disclaimer

LinkOut - more resources