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Case Reports
. 2018 Apr-Jun;13(2):195-199.
doi: 10.4103/jovr.jovr_36_16.

Intraocular Lens Calcification: Clinico-pathological Report of Two Cases and Literature Review

Mansour Rahimi  1 , Ali Azimi  1 , Masoud Hosseinzadeh  2
Affiliations
Case Reports

Intraocular Lens Calcification: Clinico-pathological Report of Two Cases and Literature Review

Mansour Rahimi et al. J Ophthalmic Vis Res. 2018 Apr-Jun.

Abstract

Purpose: We report the clinicopathological features and surgical outcomes of two cases of intraocular lens (IOL) calcification along with a review of the current literature.

Case report: The first patient was a 53-year-old woman with diabetes mellitus (type 2) who underwent phacoemulsification with posterior chamber IOL insertion (PCIOL), and pars plana vitrectomy. Significant clouding of the IOL was first noted after 1.5 years, and the IOL was replaced with an Artisan lens. The second patient was a 22-year-old woman with Vogt-Koyanagi-Harada syndrome; she underwent a lensectomy, PCIOL, and pars plana vitrectomy. IOL opacification was first noted 4.5 years after the initial surgery and the IOL was extracted.

Conclusion: The calcification of each IOL was confirmed by a pathologist. Further studies are required to determine the primary causes and mechanisms of the calcification of biomaterials including IOLs.

Keywords: Calcification; Intraocular Lens; Pathology.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Clouding of the IOL, which causes decreased vision.
Figure 2
Figure 2
IOL calcification after surgery.
Figure 3
Figure 3
The IOL was extracted and viscogoniosynechiolysis (VGS) was performed.
Figure 4
Figure 4
The slides were examined microscopically; linear deposition of round to oval coarse granular material was observed (H and E stain; ×100 magnification).
Figure 5
Figure 5
The Von Kossa stain revealed dense linear deposition of dark, calcium-containing deposits (×1200 magnification).
See this image and copyright information in PMC

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