Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 May 2;11(1):268.
doi: 10.1186/s13104-018-3356-z.

Anorectal metastasis from breast carcinoma: a case report and review of the literature

Hannes Ruymbeke  1   2 , Luc Harlet  3 , Barbara Stragier  4 , Edwin Steenkiste  5 , Merijn Ryckx  6 , Francois Marolleau  3
Affiliations
Review

Anorectal metastasis from breast carcinoma: a case report and review of the literature

Hannes Ruymbeke et al. BMC Res Notes. .

Abstract

Background: Gastrointestinal metastasis from primary breast carcinoma is uncommon, anorectal involvement is extremely rare.

Case presentation: We present the case of a 65-year old woman who underwent treatment for an infiltrative lobular carcinoma of the left breast with bone metastases and who developed metastasis of the rectum and anal canal 4 years later.

Conclusions: A patient with a history of breast cancer, especially lobular carcinoma, presenting with anorectal symptoms, should raise the suspicion of metastatic disease.

Keywords: Anorectal; Breast cancer; Gastrointestinal; Metastasis.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
MRI shows diffuse wall thickening of the rectum and infiltration of the presacral fat tissue
Fig. 2
Fig. 2
Cytomorphological and immunohistochemical features of a specimen from a lobular breast carcinoma metastasis in the anorectal lesion, obtained through endoscopy and biopsy. a, b Hematoxylin and eosin staining at various magnifications, ×5 and ×20 respectively. c Estrogen receptor positivity, magnification ×10
See this image and copyright information in PMC

References

    1. Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, et al. Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 2016;66(4):271–289. doi: 10.3322/caac.21349. - DOI - PubMed
    1. McLemore EC, Pockaj BA, Reynolds C, Gray RJ, Hernandez JL, Grant CS, et al. Breast cancer: presentation and intervention in women with gastrointestinal metastasis and carcinomatosis. Ann Surg Oncol. 2005;12(11):886–894. doi: 10.1245/ASO.2005.03.030. - DOI - PubMed
    1. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108. doi: 10.3322/caac.21262. - DOI - PubMed
    1. Arrangoiz R, Papavasiliou P, Dushkin H, Farma JM. Case report and literature review: metastatic lobular carcinoma of the breast an unusual presentation. Int J Surg Case Rep. 2011;2(8):301–305. doi: 10.1016/j.ijscr.2011.06.010. - DOI - PMC - PubMed
    1. Balakrishnan B, Shaik S, Burman-Solovyeva I. an unusual clinical presentation of gastrointestinal metastasis from invasive lobular carcinoma of breast. J Investig Med High Impact Case Rep. 2016;4(2):2324709616639723. - PMC - PubMed