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. 2018 Apr 16:46:14.
doi: 10.1186/s41182-018-0093-x. eCollection 2018.

Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001-2016)

Kyawt Mon Win  1 , Jaya Prasad Tripathy  2 , Thae Maung Maung  3 , Tin Oo  3 , Aung Thi  1 , Khin Nan Lon  4 , Zaw Lin  1
Affiliations

Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001-2016)

Kyawt Mon Win et al. Trop Med Health. .

Abstract

Background: As Myanmar progresses towards lymphatic filariasis (LF) elimination, it is important to know how well the anti-filarial activities have performed. The present study was conducted to study the implementation of the key anti-filarial activities and their impact on key indicators of LF transmission.

Methods: A secondary analysis of aggregate program data on the anti-filarial activities was conducted in four endemic state/regions of Myanmar receiving at least six mass drug administration (MDA) rounds during 2001-2016.

Results: MDA coverage has been expanded to cover all the endemic implementation units (IUs), i.e., 45 by 2015 and 6 IUs out of them have already stopped MDA. The reported coverage of MDA ranges from 87 to 100% whereas surveyed coverage ranges from 78 to 100% among the eligible population. The prevalence of microfilaria has significantly declined especially in Magway from 4.7 to 0.2% and Sagaing region from 7.9 to 1.3% during 2001-2016. Around 2.5% of estimated cases of hydrocele were reported to the program during 2009-2014.

Conclusion: Myanmar has achieved significant success in interrupting LF transmission through several MDA rounds with high coverage. However, morbidity reporting and management, being in its initial phase requires an active surveillance system for identifying and managing people with LF-associated morbidities under the program.

Keywords: Lymphatic filariasis; Mass drug administration; Myanmar.

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Conflict of interest statement

Ethics approval for this study was obtained from The Union Ethics Advisory Group (International Union against Tuberculosis and Lung Disease, Paris, France) (EAG Number: 79/16) and the Institutional Ethics Review Committee, Department of Medical Research, Myanmar (Ethics/DMR/20117/018).Not applicableThe authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Map showing lymphatic filariasis-endemic and lymphatic filariasis-non-endemic regions and MDA coverage in Myanmar, 2016. MDA = mass drug administration
Fig. 2
Fig. 2
Map showing geographical expansion of MDA coverage in lymphatic filariasis regions in Myanmar during 2001–2016. MDA = mass drug administration
Fig. 3
Fig. 3
Chronological order of anti-filarial activities in four endemic regions under the Vector Borne Control Program, Myanmar, 2001–2016
Fig. 4
Fig. 4
Trend in the prevalence of microfilaria and the overall MDA coverage after multiple MDA rounds in four endemic state/regions of Myanmar during 2001–2015. MDA = mass drug administration
Fig. 5
Fig. 5
Estimated cases versus reported cases of hydrocele in four endemic state/regions of Myanmar, 2009–14
See this image and copyright information in PMC

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