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. 2018 Apr 25:4:9.
doi: 10.1186/s40842-018-0060-9. eCollection 2018.

Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification

Rodrigo J Valderrábano  1 , Maria I Linares  1
Affiliations

Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification

Rodrigo J Valderrábano et al. Clin Diabetes Endocrinol. .

Abstract

Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic disorder that has reached worldwide epidemic proportions and is increasingly being recognized as a risk factor for fracture. Type 1 and Type 2 diabetes have different effects on bone mineral density but share common pathways, which lead to bone fragility. In this review, we discuss the available data on diabetes and fractures, bone density and the clinical implications for fracture risk stratification in current practice.

Keywords: Bone mineral density; Diabetes mellitus; Fracture; Fracture risk stratification; Osteoporosis; Type 1 diabetes mellitus; Type 2 diabetes mellitus.

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Conflict of interest statement

Not applicable.The authors have no financial or non-financial competing interests to report.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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