Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Mar 12:2018:2369430.
doi: 10.1155/2018/2369430. eCollection 2018.

Diagnosis and Management of Ovarian Tumor in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome

Yali Miao  1 , Jirui Wen  2 , Liwei Huang  3 , Jiang Wu  2 , Zhiwei Zhao  2
Affiliations
Review

Diagnosis and Management of Ovarian Tumor in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome

Yali Miao et al. Biomed Res Int. .

Abstract

In the most recent publications on Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, the uterine remnants and ovaries in patients may develop uterine remnant leiomyoma, adenomyosis, or ovarian tumor, and this can lead to problems in differential diagnosis. Here we summarize the diagnosis methods and available interventions for ovarian tumor in MRKH syndrome, with emphasis on the relevant clinical findings and illustrative relevant case. According to the clinical findings and illustrative relevant case, with the help of imaging techniques, ovarian tumors can be detected in the pelvis in patients with MRKH syndrome and evaluated in terms of size. Laparoscopy could further differentiate ovarian tumors into different pathological types. In addition, laparoscopic surgery not only is helpful for the diagnosis of MRKH combined ovarian tumor, but also has a good treatment role for excising ovarian tumor at the same time. Moreover, laparoscopic removals of ovarian tumor can be considered as a safe and reliable treatment for conservative management.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A 29-year-old female patient with primary amenorrhea. Transvaginal ultrasound shows no uterine; red arrow: polycystic ovary tumor with clear boundary.
Figure 2
Figure 2
A 29-year-old female patient with primary amenorrhea. (a) Well developed breasts. (b) Vulva. (c) Vaginal vestibule. (d) T1W1 coronary view: yellow arrow: bilateral primordial uterus and red arrow: ovary tumor. (e) T1W1 axial view: yellow arrow: bilateral primordial uterus and red arrow: ovary tumor. (f) T1W1 sagittal view: yellow arrow: vagina, blue arrow: bladder, and red arrow: ovary tumor.
Figure 3
Figure 3
(a) The right attachment was 180 degrees of torsion. (b) The right attachment. (c) After left ovarian neoplasm resection. (d) Left ovary tumor.
Figure 4
Figure 4
A 29-year-old female patient with primary amenorrhea. (a) Microscopic findings of H&E staining (×10). (b) Microscopic findings of H&E staining (×40). Morphology of calcification in ovarian cancer.
See this image and copyright information in PMC

References

    1. Morcel K., Guerrier D., Watrin T., Pellerin I., Levêque J. The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome: clinical description and genetics. Journal de Gynécologie Obstétrique et Biologie de la Reproduction. 2008;37(6):539–546. doi: 10.1016/j.jgyn.2008.07.002. - DOI - PubMed
    1. Sultan C., Biason-Lauber A., Philibert P. Mayer-Rokitansky-Kuster-Hauser syndrome: Recent clinical and genetic findings. Gynecological Endocrinology. 2009;25(1):8–11. doi: 10.1080/09513590802288291. - DOI - PubMed
    1. Girma W., Woldeyes W. Leiomyoma Arising from Mullerian Remnant, Mimicking Ovarian Tumor in a Woman with MRKH Syndrome and Unilateral Renal Agenesis. Ethiopian Journal of Health Sciences. 2015;25(4):381–384. doi: 10.4314/ejhs.v25i4.14. - DOI - PMC - PubMed
    1. Narayanan R., Mariappan S., Paulraj S., Shankar B. Imaging of leiomyomas arising from Müllerian remnants in a case of Mayer-Rokitansky-Küster-Hauser syndrome. BMJ Case Reports. 2015;2015 doi: 10.1136/bcr-2015-210737.A1522 - DOI - PMC - PubMed
    1. Kundu K., Cohen A. W., Goldberg J. Acute torsion of uterine remnant leiomyoma with Mayer-Rokitansky- Küster-Hauser syndrome. Fertility and Sterility. 2014;102(2):607–609. doi: 10.1016/j.fertnstert.2014.04.034. - DOI - PubMed

MeSH terms

Supplementary concepts

LinkOut - more resources