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Review
. 2018 Apr;13(4):573-583.
doi: 10.4103/1673-5374.230272.

Acupuncture and neuroregeneration in ischemic stroke

Affiliations
Review

Acupuncture and neuroregeneration in ischemic stroke

Qwang-Yuen Chang et al. Neural Regen Res. 2018 Apr.

Abstract

Acupuncture is potentially beneficial for post-stroke rehabilitation and is considered a promising preventive strategy for stroke. Electroacupuncture pretreatment or treatment after ischemic stroke by using appropriate electroacupuncture parameters generates neuroprotective and neuroregenerative effects that increase cerebral blood flow, regulate oxidative stress, attenuate glutamate excitotoxicity, maintain blood-brain barrier integrity, inhibit apoptosis, increase growth factor production, and induce cerebral ischemic tolerance.

Keywords: acupuncture; neuroprotection; neuroregeneration.

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Conflict of interest statement

We declare that there are no conflicts of interest associated with this manuscript and was no significant financial support that could have influenced the outcome

Figures

Figure 1
Figure 1
The acupoint that is in common use for neuroprotection or neuroregeneration in ischemic stroke. LI4: Hegu; LI10: Shousanli; LI11: Quchi; LI15: Jianyu; LI16: Jugu; ST32: Futu; ST36: Zusanli; ST37: Shangjuxu; ST40: Fenglung; SP6: Sanyinjiao; BL23: Shenshu; PC6: Neiguan; TE5: Waiguan; GB7: Qubin; GB20: Fengchi; LV3: Taichong; GV24: Chengjiang; GV4: Mingmen; GV8: Jinsuo; GV11: Shendao; GV16: Fengfu; GV20: Baihui; GV24: Shenting; GV26: Renzhong.

References

    1. Ahn SM, Kim YR, Kim HN, Shin YI, Shin HK, Choi BT. Electroacupuncture ameliorates memory impairments by enhancing oligodendrocyte regeneration in a mouse model of prolonged cerebral hypoperfusion. Sci Rep. 2016;6:28646. - PMC - PubMed
    1. Ay I, Napadow V, Ay H. Electrical stimulation of the vagus nerve dermatome in the external ear is protective in rat cerebral ischemia. Brain Stimul. 2015;8:7–12. - PMC - PubMed
    1. Bolaños JP, Almeida A. Roles of nitric oxide in brain hypoxia-ischemia. Biochim Biophys Acta. 1999;1411:415–436. - PubMed
    1. Burmester T, Hankeln T. What is the function of neuroglobin? J Exp Biol. 2009;212:1423–1428. - PubMed
    1. Cai PY, Bodhit A, Derequito R, Ansari S, Abukhalil F, Thenkabail S, Ganji S, Saravanapavan P, Shekar CC, Bidari S, Waters MF, Hedna VS. Vagus nerve stimulation in ischemic stroke: old wine in a new bottle. Front Neurol. 2014;5:107. - PMC - PubMed