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Comment
. 2018 May 4;360(6388):490-491.
doi: 10.1126/science.aat5092.

Indispensable malaria genes

John White  1 , Pradipsinh K Rathod  2
Affiliations
Comment

Indispensable malaria genes

John White et al. Science. .
No abstract available

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Figures

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A highly active malaria genome reveals many essential genes but few good drug targets.
Malaria parasites activate a large part of their genome in every life cycle stage, but high-throughput screens with millions of small molecules reveal very few “druggable” targets. Numbers in this table are approximation from references cited in the top row. Adobe stock photo (mosquito) was used in the generation of the illustration. The following restrictions apply:

  1. “Include the asset in email marketing, mobile advertising, or a broadcast program if the expected viewers is less than 500,000.”

  2. “Post the asset to a website with no limitations on viewers. If the asset is posted unmodified to a social media site, attribution is required (@ Author Name – stock.adobe.com).

  3. “Include the asset in products in a minor way, such as textbook.”

See this image and copyright information in PMC

Comment on

References

    1. WHO World Malaria Report (2017).
    1. Phillips MA et al., Nat. Rev. Dis. Primers 3, 1 (2017). - PubMed
    1. Zhang M et al., Science 360, PAGE (2018).
    1. Bushell E et al. Cell 170, 260 (2017) - PMC - PubMed
    1. Guiguemde WA et al., Chem. Biol 19, 116 (2012). - PMC - PubMed

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