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. 2018 Mar;17(1):28-31.
doi: 10.5114/pm.2018.74900. Epub 2018 Apr 11.

Does fine-needle aspiration biopsy still have a place in the diagnosis of breast lesions?

Marzanna Obrzut  1 , Marian Cholewa  2 , Jakub Baran  2 , Agnieszka Obrzut-Palusińska  3 , Ewa Kurczab  4
Affiliations

Does fine-needle aspiration biopsy still have a place in the diagnosis of breast lesions?

Marzanna Obrzut et al. Prz Menopauzalny. 2018 Mar.

Abstract

Introduction: Core needle biopsy is a preferable breast biopsy technique under ultrasound guidance. However, fine-needle biopsy is considered equally popular.

Aim of the study: To redefine the role of fine-needle aspiration biopsy (FNAB) in the diagnosis of breast lesions.

Material and methods: We retrospectively analysed the medical records of 680 patients who underwent breast ultrasound examination. In most cases, no pathologic structures were observed within the mammary glands. In 321 patients, the presence of focal lesions was revealed, and 107 patients in this group qualified for FNAB according to current recommendations. Patients with suspicious smears were referred for core needle or surgical biopsy. Patients with benign cytological smears underwent repeated ultrasound checks at 6-month intervals during the following year.

Results: All the smears were diagnostic. The vast majority of the results were categorised as benign lesions. Cancer cells were detected in six women. In one patient the lesion was classified as suspicious, probably malignant. In all of these cases, open biopsy was performed, and histopathological examination confirmed the presence of a malignant tumour. The patients were given appropriate oncological treatment. For women with benign or suspicious, but probably benign, lesions, breast ultrasound was performed twice at six-month intervals. Control tests showed no significant changes compared to the baseline examination. None of the patients required extensive additional diagnostic tests.

Conclusions: FNAB is a reliable method of assessing pathologic lesions in mammary glands.

Keywords: BI-RADS; breast lesion; fine-needle aspiration biopsy; ultrasound examination.

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Conflict of interest statement

Authors report no conflict of interest.

Figures

Fig. 1
Fig. 1
Number of examined patients within different age groups
See this image and copyright information in PMC

References

    1. Duijm LE, Groenewoud JH, Roumen RM, et al. A decade of breast cancer screening in The Netherlands: Trends in the preoperative diagnosis of breast cancer. Breast Cancer Res Treat. 2007;106:113–119. - PubMed
    1. Candelaria RP, Hwang L, Bouchard RR, et al. Breast ultrasound: current concepts. Semin Ultrasound CT MR. 2013;34:213–225. - PubMed
    1. Ajkay N, Bloomquist EV, Martin RC, et al. Fine-needle aspiration cytology in the evaluation of patients with radiographically occult, palpable breast abnormalities. Surgery. 2015;158:946–952. - PMC - PubMed
    1. Takhellambam YS, Lourembam SS, Sapam OS, et al. Comparison of ultrasonography and fine needle aspiration cytology in the diagnosis of malignant breast lesions. J Clin Diagn Res. 2013;7:2847–2850. - PMC - PubMed
    1. Stachura J, Niezabitowski A, Olszewski W, et al. Principles for the collection and analysis of thin-needle aspiration, thick-needle, and surgical bioptates, as well as material after radical breast surgery. Recommendations of the Polish Society of Pathologists, Polish Oncology Society, Polish Society of Surgeons, and Polish Society of Radiology. Med Prakt. 2001;7-8:187–195.

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