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Editorial
. 2018 Aug;66(8):1455-1458.
doi: 10.1111/jgs.15409. Epub 2018 May 4.

Can a Link Be Found Between Physical Resilience and Frailty in Older Adults by Studying Dynamical Systems?

Ravi Varadhan  1 , Jeremy D Walston  2 , Karen Bandeen-Roche  3   4
Affiliations
Editorial

Can a Link Be Found Between Physical Resilience and Frailty in Older Adults by Studying Dynamical Systems?

Ravi Varadhan et al. J Am Geriatr Soc. 2018 Aug.
No abstract available

Keywords: homeostasis; robustness; stimulation test; stressor; vulnerability.

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Figures

Figure 1
Figure 1
A hypothetical and abstract representation of possible responses of a physiological system to a clinical stressor. The solid circle (ball) represents the state of a physiological system. Under small perturbations (1a), the system establishes homeostasis and is stable. When perturbed by a stressor of sufficiently large magnitude, the system is displaced from its original state and establishes another equilibrium state. The system is robust (1b) when it maintains its functionality intact under the new equilibrium. The system is resilient (1c) when it maintains its essential functionality under the new equilibrium. The system is non-resilient (1d) when it loses its essential functionality under the new equilibrium.
Figure 2
Figure 2
The pre-stressor and post-stressor levels of function of a physiological system. A robust system (triangle) maintains its level of function; a resilient system (circle) may lose some degree of function, although it retains its essential function; a non-resilient system (square) loses its essential function.
See this image and copyright information in PMC

Comment in

References

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    1. Varadhan R, Walston J, Cappola AR, Carlson MC, Wand GS, Fried LP. Higher levels and blunted diurnal variation of cortisol in frail older women. J Gerontol A Biol Sci Med Sci. 2008;63(2):190–195. - PubMed

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