Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2018 May 3;22(5):619-620.
doi: 10.1016/j.stem.2018.04.017.

The Lysosome, Elixir of Neural Stem Cell Youth

Milos S Simic  1 , Andrew Dillin  2
Affiliations
Free article
Comment

The Lysosome, Elixir of Neural Stem Cell Youth

Milos S Simic et al. Cell Stem Cell. .
Free article

Abstract

Recently in Science, Leeman et al. find that perturbing lysosomal activity of quiescent NSCs directly impedes their ability to become activated, similar to what happens during aging. Excitingly, they could rejuvenate old quiescent NSCs by enhancing the lysosome pathway, ameliorating their ability to clear protein aggregates and become activated.

PubMed Disclaimer

Comment on

LinkOut - more resources