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Case Reports
. 2018 Winter;13(1):99-102.

Ovarian Small Cell Carcinoma: A Rare Case Report and Review of Literature

Savita Agarwal  1 , Pinki Pandey  1 , Megha Ralli  1 , Shruti Singh  1
Affiliations
Case Reports

Ovarian Small Cell Carcinoma: A Rare Case Report and Review of Literature

Savita Agarwal et al. Iran J Pathol. 2018 Winter.

Abstract

Ovarian small cell carcinoma is a rare and highly malignant tumor with poor prognosis. It usually presents in younger females with features of hypercalcemia. The exact histogenesis of the tumor is unclear and it may present as an undifferentiated tumor. In such cases, immunohistochemistry (IHC) plays an important role to confirm the diagnosis. Limited treatment options are available and mainly include radical surgery followed by adjuvant therapy in advanced stages. The current report was a rare case of small cell carcinoma of ovary presenting no symptoms of hypercalcemia diagnosed on histopathological examination and IHC findings.

Keywords: Immunohistochemistry; Ovary; Small Cell Carcinoma.

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Figures

Fig 1
Fig 1
a) Uterus and cervix measuring 10x6x3 cm.Left ovary is enlarged and measuring 27x17x12 cm. The ovarian capsule is intact and external surface was bosselated.
Fig 2
Fig 2
a)Tumor cells arranged in solid nests and focally forming rosettes along with large central areas of necrosis within the nests (H&E,100X).
Fig 3
Fig 3
Immunohistochemically profile of tumor cells: Pan CK, NSE;synaptophysin: strongly positive; chromogranin: focally positive
See this image and copyright information in PMC

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