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Review
. 2018 Jun;47(2):369-380.
doi: 10.1016/j.gtc.2018.01.008. Epub 2018 Apr 4.

Living Donor Intestinal Transplantation

Ivo G Tzvetanov  1 , Kiara A Tulla  2 , Giuseppe D'Amico  2 , Enrico Benedetti  2
Affiliations
Review

Living Donor Intestinal Transplantation

Ivo G Tzvetanov et al. Gastroenterol Clin North Am. 2018 Jun.

Abstract

Living donor intestinal transplantation (LDIT) has been improved leading to results comparable to those obtained with deceased donors. LDIT should be limited to specific indications and patient selection. The best indication is combined living donor intestinal/liver transplantation in pediatric recipients with intestinal and hepatic failure; the virtual elimination of waiting time may avoid the high mortality experienced by candidates on the deceased waiting list. Potentially, LDIT could be used in highly sensitized recipients to allow the application of de-sensitization protocols. In the case of available identical twins or HLA-identical sibling, LDIT has a significant immunologic advantage and should be offered.

Keywords: Combined living donor intestinal/liver transplantation; Intestinal failure; Living donor small bowel transplantation; Pediatric recipients.

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