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Case Reports
. 2018 Apr;72(2):154-156.
doi: 10.5455/medarh.2018.72.154-156.

Acute Coronary Syndrome With Normal Coronary Arteries: a Case of Spontaneous Spasm Lysis

Affiliations
Case Reports

Acute Coronary Syndrome With Normal Coronary Arteries: a Case of Spontaneous Spasm Lysis

Vogiatzis Ioannis et al. Med Arch. 2018 Apr.

Abstract

Introduction: Patients suffering from Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) are found with no obstructive coronary artery disease on coronary arteriography. The Aim of this interesting case report is to present a patient with acute chest pain, temporal ST-segment elevation and MINOCA.

Case report: A case of a young woman who presented with acute chest pain suggestive of angina, with temporal ST-segment elevation, accidentally recorded and not rising of myocardial necrosis biomarkers in blood tests is described. A coronary angiography via right radial artery was performed and revealed normal coronary arteries. She was defined suffering from Myocardial infarction with Non-Obstructive Coronary Arteries (MINOCA) which occurs in 1-14% of Myocardial Infarction cases. Treatment with nitrates calcium, calcium channel blockers and antiplatelet in the basis of ACS is highly indicated.

Conclusion: Coronary artery spasm is not a rare cause of ACS. Coronary angiography is indicated in all cases to exclude severe coronary heart disease.

Keywords: MINOCA; acute coronary syndrome; coronary artery spasm; unstable angina.

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Figures

Figure 1.
Figure 1.. ECG performed during chest pain episode showing a ST-segment elevation in precordial leads V1-V5 (Red arrow) which was spontaneously resolved (Black arrow), accompanied by pain relief.
Figure 2.
Figure 2.. Next day ECG developed negative T waves in precordial leads V1-V5.
Figure 3.
Figure 3.. Coronary angiography showing normal coronary arteries. A: Left Coranary Artery (LCA), B: Right Coronary Artery (RCA).

References

    1. Pasupathy S, Air T, Dreyer RP, Tavella R, Beltrame JF. Systematic review of patients presenting with suspected myocardial infarction and nonobstructive coronary arteries. Circulation. 2015;13:861–70. - PubMed
    1. Ibánez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Rev Esp Cardiol (Engl Ed) 2017;70:1082–95. - PubMed
    1. Agewall S, Beltrame JF, Reynolds HR, Niessner A, Rosano G, Caforio AL, et al. WG on Cardiovascular Pharmacotherapy. ESC working group position paper on myocardial infarction with non-obstructive coronary arteries. Eur Heart J. 2017;38:143–53. - PubMed
    1. Ong P, Athanasiadis A, Hill S, Vogelsberg H, Voehringer M, Sechtem U. Coronary artery spasm as a frequent cause of acute coronary syndrome: the CASPAR (coronary artery spasm in patients with acute coronary syndrome) study. J Am Coll Cardiol. 2008;52:523–7. - PubMed
    1. Nakayama N, Kaikita K, Fukunaga T, Matsuzawa Y, Sato K, Horio E, et al. Clinical features and prognosis of patients with coronary spasm-induced non-ST-segment elevation acute coronary syndrome. J Am Heart Assoc. 2014;3:e000795. doi: 10.1161/JAHA.114.000795. - DOI - PMC - PubMed

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