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Review
. 2018 May 8;18(6):36.
doi: 10.1007/s11892-018-0997-1.

Type 2 Diabetes in Youth: New Lessons from the SEARCH Study

Elizabeth T Jensen  1 , Dana Dabelea  2   3
Affiliations
Review

Type 2 Diabetes in Youth: New Lessons from the SEARCH Study

Elizabeth T Jensen et al. Curr Diab Rep. .

Abstract

Purpose of review: The purpose of this review is to provide an update on the recent body of evidence emerging for type 2 diabetes as identified through the SEARCH for Diabetes in Youth study.

Recent findings: This body of evidence illustrates that type 2 diabetes continues to increase in incidence, although this increase may be partially attributable to increased surveillance. Disease management is influenced by the transition from adolescent to adult care and psychosocial factors may also contribute. This evidence also describes a high prevalence of disease-associated complications and comorbidities. Risk factors for cardiovascular disease are also highly prevalent. The SEARCH for Diabetes in Youth study continues to inform our understanding of the descriptive epidemiology and natural history of type 2 diabetes in youth. As the cohort matures, new opportunities emerge for building on our understanding of how youth-onset type 2 diabetes impacts future health.

Keywords: Complications and comorbidities; Incidence; Prevalence; Risk factors.

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Conflict of interest statement

Compliance with Ethical Standards

Conflict of Interest Elizabeth T. Jensen and Dana Dabelea have no conflicts of interest to report.

Figures

Fig. 1
Fig. 1
Estimated prevalence of complications and comorbidities in type 2 diabetes at age 21 in SEARCH
See this image and copyright information in PMC

References

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    1. Dabelea D Diabetes in youth-looking backwards to inform the future: Kelly West Award Lecture 2017. Diabetes Care. 2018;41: 233–40.

      • This review presents a historical perspective of how our understanding of diabetes in youth has changed over time, including projections for future burden of disease.

    1. Hamman RF, Bell RA, Dabelea D, D’Agostino RB Jr, Dolan L, Imperatore G, et al. The SEARCH for Diabetes in Youth study: rationale, findings, and future directions. Diabetes Care. 2014;37: 3336–44.

      • This review provides a comprehensive description of the SEARCH study and proposed future directions for the study.

    1. Pettitt DJ, Talton J, Dabelea D, Divers J, Imperatore G, Lawrence JM, et al. Prevalence of diabetes in U.S. youth in 2009: the SEARCH for Diabetes in Youth study. Diabetes Care. 2014;37: 402–8.

      • This study presents the most up-to-date descriptive epidemiology for youth-onset diabetes prevalence in the U.S.

Publication types