Some mismatch repair activities in Escherichia coli
- PMID: 2974159
- PMCID: PMC282834
- DOI: 10.1073/pnas.85.24.9674
Some mismatch repair activities in Escherichia coli
Abstract
Heterozygous bacteriophage lambda DNA molecules, whose replication requires mismatch correction of a mutant nucleotide in the transcribed strand, provide an assay for localized mismatch repair in Escherichia coli. We describe two systems: one removes the A in C.A or G.A mismatches and the other removes one or the other C in a C.C mismatch. Mutations disabling the first system result in a mutator phenotype that may be identical to mutY.
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