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. 1988 Dec;85(24):9674-8.
doi: 10.1073/pnas.85.24.9674.

Some mismatch repair activities in Escherichia coli

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Some mismatch repair activities in Escherichia coli

J P Radicella et al. Proc Natl Acad Sci U S A. 1988 Dec.

Abstract

Heterozygous bacteriophage lambda DNA molecules, whose replication requires mismatch correction of a mutant nucleotide in the transcribed strand, provide an assay for localized mismatch repair in Escherichia coli. We describe two systems: one removes the A in C.A or G.A mismatches and the other removes one or the other C in a C.C mismatch. Mutations disabling the first system result in a mutator phenotype that may be identical to mutY.

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