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. 2018;113(5):e170298.
doi: 10.1590/0074-02760170298. Epub 2018 May 7.

Acute Chagas disease in the state of Pará, Amazon Region: is it increasing?

Valéria Regina Cavalcante Dos Santos  1 , Juliana de Meis  2 , Wilson Savino  2 , Jorge Alberto Azevedo Andrade  1 , José Ricardo Dos Santos Vieira  3 , José Rodrigues Coura  4 , Angela Cristina Verissimo Junqueira  4
Affiliations

Acute Chagas disease in the state of Pará, Amazon Region: is it increasing?

Valéria Regina Cavalcante Dos Santos et al. Mem Inst Oswaldo Cruz. 2018.

Abstract

Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region, with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the ingestion of contaminated food. Data on ACD in the state of Pará retrieved from 2000 to 2016 from the Brazilian Notifiable Diseases Information System (SINAN) were evaluated. During this period, 2,030 of the 16,807 reported cases were confirmed, with a higher incidence between the months of August and December, thus characterising a seasonal pattern of acute infection, and coinciding with the higher production of "açaí", one fruit likely involved in the oral transmission of the disease. Evaluation of the absolute numbers of confirmed ACD cases secondary to oral infection suggests that infection through this route increased during the 2010-2016 period, differing from what was recorded in terms of vectorial or other infection routes. These findings point to the need of intensifying strategies to prevent or substantially reduce oral transmission.

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Figures

Fig. 1
Fig. 1. distribution of acute Chagas disease cases during the period 1996-2016, in the state of Pará, Brazil. Database: Brazilian Ministry of Health Notification System (SINAN) 1996-1999. Pará state SINAN 2000-2016.
Fig. 2
Fig. 2. monthly distribution of acute Chagas disease cases confirmed during the period 2002-2016, in the state of Pará, Brazil. The middle curve indicates the mean cases, whereas the top and bottom curves depict one standard deviation. Data were retrieved from the SINAN database in the state, 2016.
Fig. 3
Fig. 3. distribution of acute Chagas disease cases regarding the putative source of infection and deaths, during the period 2002-2016, in the state of Pará, Brazil.
See this image and copyright information in PMC

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