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Comparative Study
. 2018 Jan-Dec:17:2325958218773766.
doi: 10.1177/2325958218773766.

Comparing Patient Demographics and Tumor Characteristics of HIV-Positive and HIV-Negative Patients with Cancer in South Carolina

Benjamin D Hallowell  1 , Kristina W Kintziger  2 , Wayne A Duffus  3 , John E Vena  4 , Sara W Robb  5
Affiliations
Comparative Study

Comparing Patient Demographics and Tumor Characteristics of HIV-Positive and HIV-Negative Patients with Cancer in South Carolina

Benjamin D Hallowell et al. J Int Assoc Provid AIDS Care. 2018 Jan-Dec.

Abstract

We compared the demographic and disease characteristics of HIV-positive (HIV+) and HIV-negative (HIV-) individuals with a diagnosis of cancer in South Carolina. HIV-positive patients with cancer were reflective of the HIV+ caseload in South Carolina, with HIV+ patients with cancer more likely to be male (odds ratio [OR]: 2.78: 95% confidence interval [CI]: 2.33-3.32), black (OR: 7.68; 95% CI: 6.52-9.06), and younger at cancer diagnosis (OR: 0.92; 95% CI: 0.91-0.92). Controlling for year of birth, HIV+ patients with cancer did not receive cancer diagnoses at a younger age than HIV- controls. HIV-positive individuals did not have more advanced tumor stages or grades at cancer diagnosis; however, after controlling for other factors, HIV+ individuals were still more likely to be deceased at follow-up (OR: 2.64; 95% CI: 2.20-3.17) when compared to HIV- controls. Future studies should use survival analysis methods to identify the characteristics that shorten survival among HIV+ patients with cancer.

Keywords: AIDS; AIDS-related opportunistic infections; HIV; cancer; health disparities; malignancies.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
HIV-positive patients with cancer counts by year in South Carolina.
See this image and copyright information in PMC

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