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Editorial
. 2018 Jun 1;114(7):919-921.
doi: 10.1093/cvr/cvy095.

Modelling the complexity of heart failure with preserved ejection fraction

Kevin O'Gallagher  1 , Ajay M Shah  1
Affiliations
Editorial

Modelling the complexity of heart failure with preserved ejection fraction

Kevin O'Gallagher et al. Cardiovasc Res. .
No abstract available

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Figures

Figure 1
Figure 1
Proposed framework for the investigation of HFpEF as a heterogenous condition. The patient-specific interplay among those comorbidities that are present (A) will influence the pathophysiological mechanisms at play (B). These in turn will determine the precise pattern of the clinical phenotype (C). Stratification of patients with HFpEF, both to inform underlying pathophysiology and ultimately to select effective treatment, could be based on a combination of factors (D). The selection of animal models and interpretation of data obtained in such models would be optimized by consideration of such a framework.
See this image and copyright information in PMC

Comment on

References

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