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Meta-Analysis
. 2018 May 10;17(1):108.
doi: 10.1186/s12944-018-0749-x.

Effect of dietary intervention treatment on children with iron deficiency anemia in China: a meta-analysis

Jian Sun  1 , Lei Zhang  2 , Jing Cui  3   4 , Shanshan Li  5 , Hongting Lu  2 , Yong Zhang  1 , Haiming Li  1 , Jianping Sun  6   7   8 , Zulqarnain Baloch  9
Affiliations
Meta-Analysis

Effect of dietary intervention treatment on children with iron deficiency anemia in China: a meta-analysis

Jian Sun et al. Lipids Health Dis. .

Abstract

Background: Previous studies have shown beneficial effects of dietary approaches for iron deficiency anemia (IDA) control. This study was design to investigate the effect of dietary intervention treatment on children with iron deficiency anemia.

Methods: We performed a systematic review of published dietary interventions effect on IDA treatment through meta-analysis. CBM, CNKI, Wanfang database, EMBASE, VIP, PubMed and Web of science database were searched to identify studies published between January, 1980 and December, 2016. Statistical analysis was performed by Revmen5.2 software.

Results: Initially we retrieved for 373 studies, and then 6 studies with a total of 676 individuals were included in the analysis according to the inclusion and exclusion criteria for meta-analysis. The overall pooled estimate of odds ratio [(OR), 95% confidence intervals (95% CI)] in the dietary intervention on children with iron deficiency anemia was 6.54 (95% CI: 3.48-12.31, Z = 5.82, p<0.001) and funnel plot is symmetric.

Conclusions: Our meta-analysis suggested that dietary interventions are effective in improving the iron deficiency in children with iron deficiency anemia (IDA) and should be considered in the overall strategy of IDA management.

Keywords: Children; China; Dietary intervention; Iron deficiency anemia; Meta-analysis.

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Conflict of interest statement

Ethics approval and consent to participate

NA.

Competing interests

The authors declare that they have no competing interests.

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Figures

Fig. 1
Fig. 1
Flow char diagram of participants
Fig. 2
Fig. 2
Meta-analysis of the effect of dietary intervention on children with IDA in fixed effect model
Fig. 3
Fig. 3
Stratified analysis of the effect of dietary intervention on children with IDA in random effects model
Fig. 4
Fig. 4
Funnel-plot of random control trials
See this image and copyright information in PMC

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