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Comment
. 2018 Jul;24(7):593-595.
doi: 10.1016/j.molmed.2018.04.008. Epub 2018 May 7.

Stroke Promotes Systemic Endothelial Inflammation and Atherosclerosis

Ruslan Rust  1 , Anna-Sophie Hofer  2 , Martin E Schwab  3
Affiliations
Comment

Stroke Promotes Systemic Endothelial Inflammation and Atherosclerosis

Ruslan Rust et al. Trends Mol Med. 2018 Jul.

Abstract

Patients who survive a stroke have an increased risk for recurrent vascular events. The mechanisms underlying the events are barely understood. A recent study suggests that stroke-enhanced atherosclerosis is induced through brain-released alarmins, which lead to systemic vascular inflammation and plaque formation. Interfering with these processes may lead to novel therapeutic approaches.

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