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Case Reports
. 2018 Jun:120:60-61.
doi: 10.1016/j.lungcan.2018.03.023. Epub 2018 Mar 27.

Lorlatinib - Induced pulmonary arterial hypertension

Alexandre Chabrol  1 , Marie Mayenga  2 , Abdul Momen Hamid  2 , Sylvie Friard  2 , Hélène Salvator  3 , Hélèe Doubre  2 , Séverine Fraboulet  2 , Anne-Cécile Metivier  2 , Emilie Catherinot  2 , Elisabeth Rivaud  2 , Marie Camille Chaumais  4 , David Montani  5 , Louis Jean Couderc  3 , Colas Tcherakian  6
Affiliations
Case Reports

Lorlatinib - Induced pulmonary arterial hypertension

Alexandre Chabrol et al. Lung Cancer. 2018 Jun.

Abstract

We report here the first cases, to our knowledge, of pulmonary arterial hypertension induced by lorlatinib. It s the first time that a tyrosine kinase inhibitor for lung cancer is associated with pulmonary arteriel hypertension.

Keywords: ALK rearrangement; Lorlatinib; Lung cancer; Pulmonary hypertension; Tyrosine kinase inhibitor.

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