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. 1988;74(3):195-8.
doi: 10.1007/BF01244785.

Suppression of conditioned avoidance by 8-OH-DPAT in the rat

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Suppression of conditioned avoidance by 8-OH-DPAT in the rat

M L Wadenberg et al. J Neural Transm. 1988.

Abstract

Rats were trained to perform an aversely motivated discriminative task in a shuttle-box. The conditioned avoidance response was selectively suppressed by 8-OH-DPAT in a dose-dependent manner (25-100 micrograms.kg-1). There were no statistically significant deficits in discriminative performance. The present results suggest antipsychotic-like properties of 8-OH-DPAT.

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References

    1. Physiol Behav. 1987;39(1):95-102 - PubMed
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    1. Eur J Pharmacol. 1983 May 20;90(1):151-3 - PubMed

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