Suppression of conditioned avoidance by 8-OH-DPAT in the rat
- PMID: 2974881
- DOI: 10.1007/BF01244785
Suppression of conditioned avoidance by 8-OH-DPAT in the rat
Abstract
Rats were trained to perform an aversely motivated discriminative task in a shuttle-box. The conditioned avoidance response was selectively suppressed by 8-OH-DPAT in a dose-dependent manner (25-100 micrograms.kg-1). There were no statistically significant deficits in discriminative performance. The present results suggest antipsychotic-like properties of 8-OH-DPAT.
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