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Review
. 2018 Apr 17:7:F1000 Faculty Rev-470.
doi: 10.12688/f1000research.13357.1. eCollection 2018.

Recent advances in intravenous anesthesia and anesthetics

Mohamed Mahmoud  1 , Keira P Mason  2
Affiliations
Review

Recent advances in intravenous anesthesia and anesthetics

Mohamed Mahmoud et al. F1000Res. .

Abstract

Anesthesiology, as a field, has made promising advances in the discovery of novel, safe, effective, and efficient methods to deliver care. This review explores refinement in the technology of soft drug development, unique anesthetic delivery systems, and recent drug and device failures.

Keywords: Intravenous Anesthesia; Midazolam; Propofol; Xenon.

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Conflict of interest statement

No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.

Figures

Figure 1.
Figure 1.. Structures of parent hypnotics and their carboxylic acid metabolites.
A) Methoxycarbonyl etomidate (MOC-etomidate) and MOC-etomidate’s carboxylic acid metabolite (MOC-ECA). B) Cyclopropyl-methoxycarbonyl metomidate (CPMM) and CPMM’s carboxylic acid metabolite (CPMM-CA). Permission was obtained for the reproduction of this figure.
Figure 2.
Figure 2.. Closed-loop system for hypnosis.
There are three elements in every closed-loop system: a central operating software (brain of the system), one or more target-control variables (hypnosis monitor), and one or more drug delivery systems (infusion pump). Permission was obtained for the reproduction of this figure.
See this image and copyright information in PMC

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