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Review
. 2018 Apr 5;7(2):40-49.
eCollection 2018.

The guiding role of bone metabolism test in osteoporosis treatment

Wei Zhang  1   2 , Guo-Ji Yang  3 , Shi-Xian Wu  4 , Dong-Qing Li  5 , Ying-Bo Xu  1 , Cheng-Hong Ma  1 , Jun-Ling Wang  2 , Wei-Wen Chen  1   2
Affiliations
Review

The guiding role of bone metabolism test in osteoporosis treatment

Wei Zhang et al. Am J Clin Exp Immunol. .

Abstract

Osteoporosis (OP) and osteoporotic fractures are becoming a serious health care issue in the world. Calcium and vitamin D are the basic treatment for osteoporosis. Nonetheless, they do not effectively reduce the incidences of fracture. Currently approved treatments for osteoporosis include selective estrogen receptor modulators (SERMs), bisphosphonates, denosumab, teriparatide, calcitonin and others. However, the appearance of some adverse effects including atypical fracture and breast cancer has limited long-term treatments above mentioned. Therefore, treatment decision should be made on an individual basis, taking into account the relative benefits and risks in different patients. Bone metabolism test helps to assess the patient's condition, which may ultimately lead to therapeutic options and better clinical outcomes.

Keywords: 25(OH)D; Osteoporosis; Tregs; androgen; bone turnover markers; calcitonin; calcium; cytokines; estrogen; parathyroid hormone.

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Conflict of interest statement

None.

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