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Review
. 2018 May 7:38:8.
doi: 10.1186/s41232-018-0065-x. eCollection 2018.

Periodontal Infectogenomics

Gurjeet Kaur  1 , Vishakha Grover  1 , Nandini Bhaskar  1 , Rose Kanwaljeet Kaur  1 , Ashish Jain  1
Affiliations
Review

Periodontal Infectogenomics

Gurjeet Kaur et al. Inflamm Regen. .

Abstract

Periodontal diseases are chronic infectious disease in which the pathogenic bacteria initiate the host immune response leading to the destruction of tooth supporting tissue and eventually result in the tooth loss. It has multifactorial etiological factors including local, systemic, environmental and genetic factors. The effect of genetic factors on periodontal disease is already under extensive research and has explained the role of polymorphisms of immune mediators affecting disease response. The role genetic factors in pathogens colonisation is emerged as a new field of research as "infectogenomics". It is a rapidly evolving and high-priority research area now days. It further elaborates the role of genetic factors in disease pathogenesis and help in the treatment, control and early prevention of infection. The aim of this review is to summarise the contemporary evidence available in the field of periodontal infectogenomics to draw some valuable conclusions to further elaborate its role in disease pathogenesis and its application in the clinical practice. This will open up opportunity for more extensive research in this field.

Keywords: Bacterial species; Genetics; Infectogenomics; Invasion; Microbes; Periodontitis; Proliferation.

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Conflict of interest statement

Not applicable.Not applicable.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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