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Book

Physiology, Adrenocorticotropic Hormone (ACTH)

Mary J. Allen  1 , Sandeep Sharma  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Physiology, Adrenocorticotropic Hormone (ACTH)

Mary J. Allen et al.
Free Books & Documents

Excerpt

Adrenocorticotropic hormone (ACTH) is a tropic hormone produced by the anterior pituitary. The hypothalamic-pituitary axis controls it. ACTH regulates cortisol and androgen production. Diseases associated with ACTH include Addison disease, Cushing syndrome, and Cushing disease.

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Conflict of interest statement

Disclosure: Mary Allen declares no relevant financial relationships with ineligible companies.

Disclosure: Sandeep Sharma declares no relevant financial relationships with ineligible companies.

References

    1. Houngbadji MSTS, Niang B, Boiro D, Mbaye A, Seck A, Ndongo AA, Ly ID, Ndiaye O. [Adrenocorticotropic hormone (ACTH) insensitivity syndrome: about a case]. Pan Afr Med J. 2018;30:244. - PMC - PubMed
    1. Patti G, Guzzeti C, Di Iorgi N, Maria Allegri AE, Napoli F, Loche S, Maghnie M. Central adrenal insufficiency in children and adolescents. Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):425-444. - PubMed
    1. Fredette ME, Topor LS. Case 3: Emesis and Oral Hyperpigmentation in a 17-year-old Girl. Pediatr Rev. 2018 Aug;39(8):421-423. - PubMed
    1. Miller WL. The Hypothalamic-Pituitary-Adrenal Axis: A Brief History. Horm Res Paediatr. 2018;89(4):212-223. - PubMed
    1. Shumiloff NA, Lam WM, Manasco KB. Adrenocorticotropic hormone for the treatment of West Syndrome in children. Ann Pharmacother. 2013 May;47(5):744-54. - PubMed

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