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Comment
. 2018 May 14;33(5):789-790.
doi: 10.1016/j.ccell.2018.04.006.

A-to-I RNA Editing: An Overlooked Source of Cancer Mutations

Shay Ben-Aroya  1 , Erez Y Levanon  2
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A-to-I RNA Editing: An Overlooked Source of Cancer Mutations

Shay Ben-Aroya et al. Cancer Cell. .
Free article

Abstract

RNA editing is a source of transcriptomic diversity, mainly in non-coding regions, and is found to be altered in cancer. In this issue of Cancer Cell, Peng et al. show that RNA editing events are manifested at the proteomic levels and are a source of cancer protein heterogeneity.

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  • A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.
    Peng X, Xu X, Wang Y, Hawke DH, Yu S, Han L, Zhou Z, Mojumdar K, Jeong KJ, Labrie M, Tsang YH, Zhang M, Lu Y, Hwu P, Scott KL, Liang H, Mills GB. Peng X, et al. Cancer Cell. 2018 May 14;33(5):817-828.e7. doi: 10.1016/j.ccell.2018.03.026. Epub 2018 Apr 26. Cancer Cell. 2018. PMID: 29706454 Free PMC article.

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